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class=\"wp-block-paragraph\">65\u6b73\u4ee5\u4e0a\u306e\u65b9\u306f\u3001\u516c\u8cbb\u306e\u52a9\u6210\u304c\u3042\u308b\u5b9a\u671f\u63a5\u7a2e\u306e\u5bfe\u8c61\u3067\u3059\u3002<br>60\u301c64\u6b73\u3067\u3082\u3001\u5fc3\u81d3\u30fb\u814e\u81d3\u30fb\u547c\u5438\u5668\u306a\u3069\u306b\u91cd\u3044\u969c\u5bb3\u306e\u3042\u308b\u65b9\u306f\u5bfe\u8c61\u306b\u306a\u308a\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u9ad8\u9f62\u306e\u65b9\u5411\u3051\u306b\u306f\u3001\u300c\u9ad8\u7528\u91cf\u30ef\u30af\u30c1\u30f3\u300d\u3082\u3042\u308a\u307e\u3059\u3002<br>\u30ef\u30af\u30c1\u30f3\u306e\u6210\u5206\u3092\u901a\u5e38\u306e4\u500d\u306b\u5897\u3084\u3057\u3001\u8155\u306e\u7b4b\u8089\u306b\u6ce8\u5c04\u3059\u308b\u30bf\u30a4\u30d7\u3067\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u6d77\u5916\u306e65\u6b73\u4ee5\u4e0a\u3092\u5bfe\u8c61\u306b\u3057\u305f\u5927\u898f\u6a21\u306a\u8a66\u9a13\u3067\u306f\u3001<br>\u901a\u5e38\u306e\u30ef\u30af\u30c1\u30f3\u3088\u308a\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u304c24.2\uff05\u5c11\u306a\u304b\u3063\u305f\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br>\uff08DiazGranados \u307b\u304b\u3001New England Journal of Medicine\u30012014\u5e74\uff09<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u65e5\u672c\u3067\u30822024\u5e7412\u6708\u306b\u627f\u8a8d\u3055\u308c\u3001<br>\u4eca\u5e7410\u6708\u304b\u308975\u6b73\u4ee5\u4e0a\u306e\u5b9a\u671f\u63a5\u7a2e\u306b\u52a0\u308f\u308b\u4e88\u5b9a\u3067\u3057\u305f\u3002<br>\u3068\u3053\u308d\u304c\u88fd\u9020\u4e0a\u306e\u7406\u7531\u3067\u767a\u58f2\u304c\u5ef6\u671f\u3055\u308c\u3001<br>\u4eca\u30b7\u30fc\u30ba\u30f3\u306e\u5b9a\u671f\u63a5\u7a2e\u306f\u3001\u3053\u308c\u307e\u3067\u3068\u540c\u3058\u30ef\u30af\u30c1\u30f3\u3067\u884c\u308f\u308c\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u300c\u65b0\u3057\u3044\u30ef\u30af\u30c1\u30f3\u3092\u6253\u3061\u305f\u3044\u300d\u3068\u3054\u5bb6\u65cf\u306b\u805e\u304b\u308c\u305f\u3089\u3001<br>\u4eca\u30b7\u30fc\u30ba\u30f3\u306f\u307e\u3060\u4f7f\u3048\u306a\u3044\u3001\u3068\u304a\u4f1d\u3048\u3044\u305f\u3060\u3051\u308c\u3070\u3068\u601d\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u4e16\u754c\u3067\u306f\u3001\u6b21\u306e\u4e16\u4ee3\u306e\u30ef\u30af\u30c1\u30f3\u304c\u52d5\u304d\u51fa\u3057\u3066\u3044\u307e\u3059<\/h2>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u306e\u9805\u76ee\u3067\u7d39\u4ecb\u3059\u308b\u30ef\u30af\u30c1\u30f3\u306f\u3001\u3044\u305a\u308c\u3082<strong>\u65e5\u672c\u3067\u306f\u627f\u8a8d\u3055\u308c\u3066\u304a\u3089\u305a\u3001\u5f53\u9662\u3067\u3082\u63a5\u7a2e\u3067\u304d\u307e\u305b\u3093<\/strong>\u3002<br>\u4e16\u754c\u306e\u7814\u7a76\u306e\u52d5\u304d\u3068\u3057\u3066\u3001\u304a\u8aad\u307f\u304f\u3060\u3055\u3044\u3002<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">mRNA\u30ef\u30af\u30c1\u30f3<\/h3>\n\n\n\n<p class=\"wp-block-paragraph\">\u65b0\u578b\u30b3\u30ed\u30ca\u3067\u5b9f\u7528\u5316\u3055\u308c\u305f\u6280\u8853\u304c\u3001\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306b\u3082\u4f7f\u308f\u308c\u59cb\u3081\u307e\u3057\u305f\u3002<br>2026\u5e748\u6708\u3001\u30a2\u30e1\u30ea\u30ab\u306750\u6b73\u4ee5\u4e0a\u5411\u3051\u306b\u521d\u3081\u3066\u627f\u8a8d\u3055\u308c\u3066\u3044\u307e\u3059\u3002<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">4\u4e07\u4eba\u3092\u8d85\u3048\u308b\u8a66\u9a13\u3067\u306f\u3001\u5f93\u6765\u306e\u30ef\u30af\u30c1\u30f3\u3068\u6bd4\u3079\u3066\u3001<br>\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6\u306b\u304b\u304b\u3063\u305f\u4eba\u304c26.6\uff05\u5c11\u306a\u304b\u3063\u305f\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br>\uff08New England Journal of Medicine\u30012026\u5e74\uff09<br>\u5225\u306e\u4f1a\u793e\u306e18\u301c64\u6b73\u3092\u5bfe\u8c61\u306b\u3057\u305f\u8a66\u9a13\u3067\u3082\u300134.5\uff05\u3068\u3044\u3046\u7d50\u679c\u3067\u3057\u305f\u3002<br>\uff08Fitz-Patrick \u307b\u304b\u3001New England Journal of Medicine\u30012025\u5e74\uff09<\/p>\n\n\n\n<p class=\"wp-block-paragraph\">\u3053\u3053\u3067\u5927\u5207\u306a\u306e\u306f\u3001\u3053\u308c\u304c\u300c\u5f93\u6765\u306e\u30ef\u30af\u30c1\u30f3\u3068\u306e\u6bd4\u8f03\u300d\u3060\u3068\u3044\u3046\u70b9\u3067\u3059\u3002<br>\u300c\u6253\u3066\u307026.6\uff05\u9632\u3052\u308b\u300d\u3067\u306f\u306a\u304f\u3001<br>\u300c\u4eca\u306e\u30ef\u30af\u30c1\u30f3\u306b\u4e0a\u4e57\u305b\u3057\u3066\u3001\u3055\u3089\u306b\u7d044\u5206\u306e1\u6e1b\u3089\u305b\u305f\u300d\u3068\u3044\u3046\u610f\u5473\u3067\u3059\u3002<\/p>\n\n\n\n<p 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class=\"wp-block-paragraph\">\u4eca\u306e\u30ef\u30af\u30c1\u30f3\u306e\u591a\u304f\u306f\u3001\u9d8f\u306e\u5375\u306e\u4e2d\u3067\u30a6\u30a4\u30eb\u30b9\u3092\u5897\u3084\u3057\u3066\u4f5c\u308a\u307e\u3059\u3002<br>\u305d\u306e\u904e\u7a0b\u3067\u30a6\u30a4\u30eb\u30b9\u304c\u5c11\u3057\u5909\u5316\u3057\u3001\u6d41\u884c\u306e\u578b\u3068\u305a\u308c\u308b\u3053\u3068\u304c\u3042\u308a\u307e\u3059\u3002<br>\u6d77\u5916\u3067\u306f\u3001\u7d30\u80de\u3084\u907a\u4f1d\u5b50\u7d44\u63db\u3048\u306e\u6280\u8853\u3067\u4f5c\u308b\u30ef\u30af\u30c1\u30f3\u3082\u4f7f\u308f\u308c\u3066\u3044\u307e\u3059\u3002<br>\u907a\u4f1d\u5b50\u7d44\u63db\u3048\u306e\u30ef\u30af\u30c1\u30f3\u3067\u306f\u300150\u6b73\u4ee5\u4e0a\u3067\u5f93\u6765\u3088\u308a30\uff05\u5c11\u306a\u304b\u3063\u305f\u3068\u5831\u544a\u3055\u308c\u3066\u3044\u307e\u3059\u3002<br>\uff08Dunkle \u307b\u304b\u3001New England Journal of Medicine\u30012017\u5e74\uff09<\/p>\n\n\n\n<h3 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class=\"wp-block-paragraph\">\u672c\u8a18\u4e8b\u306f\u4e00\u822c\u7684\u306a\u60c5\u5831\u63d0\u4f9b\u3092\u76ee\u7684\u3068\u3057\u305f\u3082\u306e\u3067\u3001\u500b\u3005\u306e\u8a3a\u65ad\u3084\u6cbb\u7642\u65b9\u91dd\u3092\u793a\u3059\u3082\u306e\u3067\u306f\u3042\u308a\u307e\u305b\u3093\u3002\u5185\u5bb9\u306f\u63b2\u8f09\u6642\u70b9\u306e\u60c5\u5831\u306b\u3082\u3068\u3065\u3044\u3066\u3044\u307e\u3059\u3002\u75c7\u72b6\u306e\u3042\u3089\u308f\u308c\u65b9\u3084\u3001\u691c\u67fb\u30fb\u6cbb\u7642\u306e\u5fc5\u8981\u6027\u306f\u60a3\u8005\u3055\u3093\u3054\u3068\u306b\u7570\u306a\u308a\u307e\u3059\u3002\u8a18\u8f09\u3057\u305f\u691c\u67fb\u3084\u85ac\u5264\u306e\u4f7f\u7528\u306b\u306f\u533b\u5e2b\u306e\u8a3a\u5bdf\u304c\u5fc5\u8981\u3067\u3001\u8cbb\u7528\u306f\u8a3a\u7642\u5185\u5bb9\u306b\u3088\u3063\u3066\u7570\u306a\u308a\u307e\u3059\u3002\u3054\u4e0d\u660e\u306a\u70b9\u306f\u5f53\u9662\uff08\u96fb\u8a71 092-791-3985\uff09\u307e\u3067\u304a\u554f\u3044\u5408\u308f\u305b\u304f\u3060\u3055\u3044\u3002<\/p>\n<\/div><\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<h2 class=\"wp-block-heading\">\u4eca\u56de\u306e\u8a18\u4e8b\u306e\u6839\u62e0<\/h2>\n\n\n\n<div class=\"wp-block-group ftz-src\"><div class=\"wp-block-group__inner-container is-layout-flow wp-block-group-is-layout-flow\">\n<ul class=\"wp-block-list\">\n<li>Demicheli V, et al. Vaccines for preventing influenza in healthy adults. Cochrane Database Syst Rev. 2018;2:CD001269.<\/li>\n\n\n\n<li>Monto AS, et al. Comparative efficacy of inactivated and live attenuated influenza vaccines. N Engl J Med. 2009;361:1260-7.<\/li>\n\n\n\n<li>\u4e2d\u91ce\u8cb4\u53f8\u300c\u8fd1\u5e74\u308f\u304c\u56fd\u3067\u5c0e\u5165\u3055\u308c\u305f\u65b0\u3057\u3044\u30ef\u30af\u30c1\u30f3\u306b\u3064\u3044\u3066\u300d\u5c0f\u5150\u8033\u9f3b\u54bd\u5589\u79d1 2025;46(2):69-76.<\/li>\n\n\n\n<li>DiazGranados CA, et al. Efficacy of high-dose versus standard-dose influenza vaccine in older adults. N Engl J Med. 2014;371:635-45.<\/li>\n\n\n\n<li>Dunkle LM, et al. Efficacy of recombinant influenza vaccine in adults 50 years of age or older. N Engl J Med. 2017;376:2427-36.<\/li>\n\n\n\n<li>Fitz-Patrick D, et al. Efficacy, Immunogenicity, and Safety of Modified mRNA Influenza Vaccine. N Engl J Med. 2025.<\/li>\n\n\n\n<li>Efficacy and Safety of an mRNA Seasonal Influenza Vaccine in Adults. N Engl J Med. 2026.<\/li>\n\n\n\n<li>\u539a\u751f\u52b4\u50cd\u7701\u300c\u30a4\u30f3\u30d5\u30eb\u30a8\u30f3\u30b6Q&amp;A\u300d<\/li>\n\n\n\n<li>\u798f\u5ca1\u770c\u300c\u798f\u5ca1\u770c\u611f\u67d3\u75c7\u767a\u751f\u52d5\u5411\u8abf\u67fb\u611f\u67d3\u75c7\u9031\u5831\u300d\u4ee4\u548c8\u5e74\u7b2c38\u9031\uff08\u4ee4\u548c8\u5e749\u670828\u65e5\u516c\u8868\uff09<\/li>\n<\/ul>\n<\/div><\/div>\n\n\n\n<hr class=\"wp-block-separator has-alpha-channel-opacity\"\/>\n\n\n\n<p>\u8a3a\u5bdf\u306e\u3054\u4e88\u7d04\u306f\u3053\u3061\u3089\u304b\u3089\ud83c\udf3f<\/p>\n<p><a class=\"ftz-cta\" href=\"https:\/\/patient.digikar-smart.jp\/institutions\/626d04ef-a5e9-49cf-bb68-8a2644ee4661\/reserve\" target=\"_blank\" rel=\"noopener\">\u3054\u4e88\u7d04\u306f\u3053\u3061\u3089<\/a><\/p>\n<p>\u4e0b\u8a18\u3088\u308a\u30c7\u30b8\u30b9\u30de\u8a3a\u5bdf\u5238\u30a2\u30d7\u30ea\u306e\u30c0\u30a6\u30f3\u30ed\u30fc\u30c9\u3082\u5927\u5909\u4fbf\u5229\u3067\u3059\u3002<\/p>\n<p><a class=\"ftz-app\" 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